Anti-human CD3 Monoclonal Antibody (OKT3)

  • Product ID:

    B104- 0005、B104-0010

  • Specifications:

    0.5mg,1mg

  • Application:

    Special design for the activation and expansion of cultured human T cells.

  • Feature:

    High quality protein, 1mg/vial, white lyophilized powder.

- Product Overview -

Product Description: 
The product is a monoclonal antibody against human CD3 molecule which expressed on mature T   cell. In mammals, CD3 combines with TCR and CD247 molecules to form TCR-CD3 complex and then mediates T cell activation. CD3 molecule is composed of one γ chain, one δ chain and two ε  chains, and is responsible for the singnaling transduction for T cell activation. Therefore, T cells also can be directly induced into actiavation and proliferation by antibodies (such as  O KT3  ) targeted CD3 molecule.The target epitope recognized by  OKT3  is the ε  chain of CD3.   O KT3  reacts with all peripheral T cells and CD3+ thymocytes in human. This product is s  uitable for the activation  and expansion of T lymphocytes. 


Application:  
Special design for the activation and expansion of cultured human T   cells.


Storage:

Keep at - 20 to - 70 ℃ in lyophilized form.
After dissolution, it shall be s ub-packed and stored at - 20 to - 70 ℃. Avoid repeated freezing and thawing.


Specification:
High quality protein, 1mg/vial, white lyophilized powder.


Dosage instructions for use: 
Diluted with PBS or sterile water. It is recommended for T cell activation in vitro at concentration of 100ng / ml, and suggets that each laboratory optimize its concentration for culture. 


Shelf life:
Store under specified conditions for 24 months.
The diluted CD3 solution can be stored at 2-8 ℃ for one month.